The "Bag-in/Bag-out" (BIBO) HEPA filter housing system is designed for exhaust sytems with high requirements as regards to tightness and contamination free changing of filter elements such as medical, pharmaceutical and nuclear facilities, BSL 3 & 4 laboratories, etc.

The Krantz "Bag-in/Bag-out" HEPA filter housing system with bubble tight dampers was first installed at Public Health Laboratory in 2000 This system has been installed at all BSL 3/4 laboratories and indoor shooting ranges in Hong Kong.